Background: Mucins, a family of heavily glycosylated proteins (glycoproteins) produced by epithelial tissues in most organisms, usually have a well-defined expression pattern, which can be disrupted in response to certain contingencies especially to injuries and/or challenges. The purpose of this Study was to characterize the spectrum of Mucins and genes associated with the maintenance of mucosal linings expressed in Actinia tenebrosa and describe their evolutionary relatedness with more complex metazoan homologs as well as profile their expression and protein abundance inresponse biotic and abiotic stimuli. Samples of Actinia tenebrosa collected from Queensland were housed in standard aquarium conditions to replicate their natural habitat. They were then subjected to different treatments of aerial exposure and bacterial challenge, and their multiple transcriptomes were sequenced on an Illumina Nextseq 500 using paired end chemistry and analysed with a standardised bioinformatic pipeline. It was observed that mucin genes in Actinia Tenebrosa are well suited to dynamic changes, the function of mucin genes, the number of it,Distribution of mucin genes and genes associated with maintenance of mucousal linings in Cnidarians are varied and adaptable to changes in biotic and abiotic changes in the environment.
Keywords: Mucin Protein,PTS ddomain,VWD domain,VWC domain,Mucin in cindarians and Actinia Tenebrosa
Objective: Identification and characterization of mucin genes and genes involved in mucousal lining maintenance in A. Tenebrosa and the evolution of these genes across cnidarians and metazoans.