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Question 1. The following physiological processes are important for blood glucose control:
 Insulin synthesis and release
Insulin binding to target tissues Explain how they are different in your person/client in comparison to a healthy non-diabetic person.
Question 2. The following are some consequences of long-term poorly controlled hyperglycaemia:
 Neuropathy
 Myocardial infarction Explain why they may occur in your person/client.
Question 3. The following drugs are used in the management of type II diabetes mellitus.
 Metformin
 Discuss why it can be used by your person/client by referring to its mechanism of action.
Question 4. Answer both parts (a) and (b)
(a) Insulin resistance can occur in a person with increased abdominal adiposity. Explain the pathophysiological basis for this.
 (b) Explain why HbA1c is used a measure of long-term control of blood glucose levels and how this measure will be useful in the management of your person’s/client’s disease.

Biology

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