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Background. The glycoprotein IIb/IIIa antagonists (GPAs) represent a new class of drugs to prevent platelet aggregation in the acute treatment of non-ST-elevation acute coronary syndromes (ACS). Rapid reviews of GPAs for this indication have identified serious limitations in published cost-effectiveness analyses, including a dearth of cost-effectiveness estimates using life-years or quality-adjusted life-years (QALYs) as measures of effectiveness; a lack of UK-specific studies which reflect ...

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