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Define chromatid: How DNA Exchange Between Chromatids Increases Genetic Diversity

Referencing Styles : MLA | Pages : 2

Define chromatid.

A chromatid may be a body that has been new derived or the copy of such a chromosome, the 2 of them still joined to the first body by one body structure. When a cell is making ready to divide, it makes a replacement copy of its entire DNA, in order that the cell currently possesses two copies of chromosome.

Before replication, one chromosome consists of one polymer molecule. Following replication, everybody consists of two polymer molecules; in alternative words, polymer replication itself will increase the quantity of DNA however does not (yet) increase the amount of chromosomes. The two identical copies each forming one-half the replicated chromosomes are referred to as chromatids. Throughout the later stages of organic process, these chromatids separate lengthwise to become individual chromosomes.

Chromatid pairs are ordinarily genetically identical and same to be homozygous; but, if mutation(s) occur, they will gift slight variations, within which case they are heterozygous. The pairing of chromatids should not be confused with the ploidy of an organism, that is that the range of homologous versions of a chromosome.

Sister chromatids:

Chromatids could also be sister or non-sister chromatids. A sister strand is either one in every one of the two chromatids of an equivalent body joined along by a standard bodily structure. A combine of sister chromatids is named a span. Once sister chromatids have separated (during the phase of cell division of cell division or the anaphase II of meiosis throughout sexual reproduction), they are once more known as chromosomes, every having an equivalent genetic very mutually of the individual chromatids that created up its parent. The DNA sequence of two sister chromatids is totally identical (apart from terribly rare DNA repetition errors).

How can one tell sister chromatids apart from homologous chromosomes.

Most organisms have DNA as their genetic material. Diploid organisms like humans bear two copies of comparable chromosomes. These are called homologous chromosomes. Throughout metaphase I of meiosis I, homologous chromosomes seem in pairs. Sister chromatids are the two precise copies that are fashioned by the replication of one polymer molecule at the S part of the interphase. The key distinction between homologous chromosomes and sister chromatids is that homologous chromosomes might not carry identical info all the time whereas sister chromatids carry identical information all the time.


Homologous chromosomes are made up of both maternal and paternal chromosomes but the Sister chromatids are made up of either a maternal or paternal chromosome. Homologous chromosomes may contain same or different alleles of the same gene. Thus, the gene sequence is not identical at all the times the Sister chromatids contain identical gene sequence throughout the chromatids except in the chromosomal crossover. Homologous chromosomes appear in the metaphase I of meiosis Sister Chromatids and I are formed during the DNA replication in the S phase of interphase. Homologous chromosomes do not stick together. They exist in pairs as comparison Sister Chromatids are joined together by their centromere. Homologous chromosomes are composed of four DNA strands. Single sister chromatid is composed of a single DNA strand. Homologous chromosomes are segregated during the anaphase I of meiosis I but Sister Chromatids are separated from their centromere during anaphase II of meiosis II and the anaphase of mitosis. Homologous chromosomes allow random segregation of chromosomes and genetic recombination during metaphase I. Sister chromatids allow random segregation of chromatids and chromosomal crossover during metaphase II of meiosis and metaphase of mitosis.

Explain how DNA exchange between chromatids increases genetic diversity. 

Although we tend to are all-distinctive, there are usually obvious similarities inside families. Perhaps you do have constant nose as your brother or red hair like your mother. Family similarities occur, as a result of we tend to inherit traits from our folks (in the shape of the genes that contribute to the traits). His passing of genes from one generation to succeeding is named heredity. Straightforward organisms die genes by duplicating their genetic data and so cacophonic to make a uniform organism. Additional advanced organisms, together with humans, manufacture specialised sex cells (gametes) that carry 1/2 the genetic data, then mix these to make new organisms. The method that produces gametes is named meiosis.


Meiosis makes sperm and eggs:

During meiosis in humans, one diploid cell (with 46 chromosomes or 23 pairs) undergoes 2 cycles of cell division but only one round of DNA replication. The result is four haploid daughter cells known as gametes or egg and sperm cells (each with 23 chromosomes – 1 from each pair in the diploid cell).

At conception, an egg cell and a sperm cell combine to form a zygote (46 chromosomes or 23 pairs). This is the first cell of a new individual. The halving of the number of chromosomes in gametes ensures that zygotes have the same number of chromosomes from one generation to the next. This is critical for stable sexual reproduction through successive generations.

Genetic variation is increased by meiosis:

During fertilization, one gamete from each parent combines to form a zygote. Because of recombination and independent assortment in meiosis, each gamete contains a different set of DNA. This produces a unique combination of genes in the resulting zygote.

Recombination or crossing over occurs during prophase I. Homologous chromosomes – 1 inherited from each parent – pair along their lengths, gene by gene. Breaks occur along the chromosomes, and they rejoin, trading some of their genes. The chromosomes now have genes in a unique combination.


Independent assortment is the process where the chromosomes move randomly to separate poles during meiosis. A gamete will end up with 23 chromosomes after meiosis, but independent assortment means that each gamete will have one of many different combinations of chromosomes.

This reshuffling of genes into unique combinations increases the genetic variation in a population and explains the variation we see between siblings with the same parents.


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