A series of rhythmic, involuntary, contraction and relaxation of muscles is known as clonus. It is a Greek term which means “violent, confused motion”. Clonus can be considered to be a sign of certain conditions which targets the neurological anatomy, and it has the association with the neuron lesions of the upper motor and involve in descending the pathways of the motor. In most cases, spasticity accompanies the clonus. Large motions are caused in clonus, which is initiated by a reflex, and it is not like the spontaneous small twitches like fasciculation. On average, the beat frequency of clonus range from three to eight Hz, which may last from a few seconds to some minutes, which solely depends on the patient’s condition.
Typically clonus is observed in people suffering from stroke, cerebral palsy, multiple sclerosis, hepatic encephalopathy and spinal cord damage. Ingesting with serotonergic drugs also result in clonus where the ingestion predicts the impending serotonin toxicity. Serotonin syndrome is a reaction which occurs due to excessive drug abuse or high medication dosage. A tumour in the brain pushes the neuron motor and can lead to swelling in the brain, thus can lead to clonus.
In the ankle, the Clonus is tested by flexing the foot rapidly in Dorsiflexion motion, and the Gastrocnemius muscle is stretched. If the foot beats subsequently, it is considered to be abnormal, which is in the case of sustained clonus. In the knees, clonus is detected by pushing patella or the knee cap rapidly in the direction of toes.
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