fb
$20 Bonus + 25% OFF
$20 Bonus + 25% OFF
Securing Higher Grades Costing Your Pocket? Book Your Assignment at The Lowest Price Now!
loader
Add File

Error goes here

Files Missing!

Please upload all relevant files for quick & complete assistance.

Stuck on Your Question?

Get 24x7 live help from our Top Tutors. All subjects covered.

250 words

Error goes here

Students Who Viewed This Also Studied

15 Pages
Manage Clinical Innovation

Title: Annotated Literature Review (Remote Dispensing unit/pharmacy) Type: Annotated Literature Review Word Limit: Minimum 1000 words Maximum 1200 words References: Minimum of 15 references Task Descr ...

Type

Assignment

Subject

Pharmacy

7 Pages
401006 Bioscience

1.1 What is the organism that causes tetanus and why is it of concern in this situation?1.2 Discuss the rationale for giving Mary the tetanus booster.  2. Physiological basis of the three wound o ...

Course

401006

Type

Case Study

Subject

Pharmacy

University

Western Sydney University

3 Pages
Humanities

The assignment requires writing up an ethics essay based on a medical case we have encountered. So far I have two cases that raised ethical questions that I could use. One about euthanasia and another ...

Type

Essays

Subject

Pharmacy

6 Pages
Medical

1. A patient requiring a PEG feed has their digoxin tablets converted to an elixir. The doctor has converted the dose appropriately and prescribed the elixir in the drug chart below. Using the drug ch ...

Type

Assignment

Subject

Pharmacy

PHAR1101 Introduction to Pharmacy and Formulation Sciences

Question

Answered

Questions:

1.

As part of your honours research lab-based project, you are required to validate an HPLC method for assaying a drug in capsules. Refer to the ICH and/or PIC/s website and answer the following questions:

  1. Explain the role of PIC/s and the benefits to the pharmaceutical industry (in Australia) by the TGA joining PIC/s.
  2. Briefly explain the ICH requirements to validate the HPLC assay of an active ingredient in the capsules in terms of precision.
  3. The harmonised “Guide to good manufacturing practice for medicinal products” (Part 1 – developed by PIC/s on July 2018 - PE 009-14) has been adopted by the TGA. Briefly describe the role of QC in the GMP of the manufacture of medicine outlining two examples (processes) for QC.
  4. Refer to the following diagram from Tyrer et al., 1970 (Outbreak of Anticonvulsant Intoxication in an Australian City – available in your reading list in module 1). Discuss how the root cause of the intoxication of phenytoin was identified and then explain how applying the GMP principles should avoid such incident. 

 

2.

Review the following case and then answer the following questions:

The Australian sponsor of specific tablets has been notified by the overseas manufacturer that distributed finished product has had minor non-compliances identified pertaining to marginally lower potency (assay) and dissolution times for the tablets during routine stability testing.
There is no health or safety risk to any patient/consumer if they take these goods. This recall action does not affect any other batches of these tablets. These batches have been distributed to pharmacies and warehouses. No injuries have occurred in Australia due to this and this matter is not considered to be safety related.

  1. Explaining your selection, select an appropriate recall action for this incident.
  2. Classify the recall action and justify your classification. 

3.

The UV-Visible spectrometer can be used in the pharmaceutical industry due to its simple use, relative affordability, and wide application. Answer the following questions:

  1. Briefly explain the use of the UV-Visible spectrometer in the qualitative analysis of active pharmaceutical ingredients in medicine.
  2. Outline the analytical steps needed to be taken when using the UV-Visible spectrometer to quantify a drug in medicine and briefly explain three factors that need to be considered to ensure accurate measurement from the instrument.
  3. What is the concentration of drug X in a solution in (in mg per mL) if value for drug X is 500 at a specific wavelength and the measured absorbance was 0.250 at the same wavelength?
  4. Calculate the percentage of stated content of drug X in tablets from the following information:

(i) Tablet powder containing about 80 mg of the drug is ground to a paste with 10 ml of 2 M HCl.

(ii) The paste is then diluted with 200 ml of water, shaken for 15 min and finally made up to 500 mL.

(iii) A portion of the extract is filtered.

(iv) 2.5 mL of the filtrate is taken and diluted to 50 ml with 0.1 M HCl.

(v) The absorbance is read at a wavelength of 251 nm.

Note the followings:

  • value of drug X at 251 nm = 935
  • Stated content of drug X per tablet = 50 mg
  • Weight of 20 tablets = 1.650 g
  • Weight of tablet powder taken for assay = 0.1360 g
  • Absorbance reading = 0.500.

4.

Refer to the Table that summarises the requirements and sections of the TGO 101 that applies to different types of medicines (page 9 in Guidance for TGO 101 V1.1 February 2020 – Reading list for Module 3) and then answer the following questions:

  1. Identify FOUR minimum requirements for Amoxilcapsules (500 mg) and describe the required criteria to pass each test.
  2. If we are to do the uniformity of mass of single unit dose for Amoxil capsules, outline the steps needed to complete the test.
  3. The assay of 10 individual capsules which were selected randomly from a batch of Amoxilcapsules (500 mg) was conducted and is shown in the table below. Answer the following questions:

  1. Explaining your answer, state whether the batch of capsules pass/fail/need further testing for the uniformity of content. You need to explain your answer.
  2. Showing your work and explaining your answer, state whether the same batch (results shown in the table above) pass/fail/need further testing for the uniformity of dosage unit.
  3. Explain the two approaches for completing the uniformity of dosage unit and the conditions for applying each approach in your answer. Your answer should include an example medicine where each approach must be followed for the uniformity of dosage unit.

5.

Your pharmacy undertakes extemporaneous compounding regularly to meet the needs of your customers. To comply with the current Quality Care guidelines, your pharmacy has decided to undertake quality control (QC) tests of the products regularly compounded at the pharmacy.

You have chosen the salicylic acid and coal tar ointment as the product to be checked. Salicylic acid and coal tar ointment APF is prepared by using the following excipients.

  1. You have decided to contact Professional Compounding Chemists of Australia (PCCA) to request QC testing of your products. Explain FOUR tests that PCCA will consider completing to meet QC requirements for the ointment that you have prepared. Your answer should include the importance of each test.
  2. Texture probe analyser is frequently used in the quality assurance of pharmaceuticals. Explain THREE QC parameters that can be obtained from this instrument and outline how these parameters can be used to assure the quality of semi-solid formulations. Your answer should explain how these parameters are obtained i.e. experiment method and typical results obtained from this instrument.
  3. Semi-solid dosage forms can be used to deliver medication via wide range of routes. Using topical drug delivery and ocular drug delivery as examples, explain how the quality control tests used for semi-solid dosage forms may differ depending on route of drug delivery.

PHAR1101 Introduction to Pharmacy and Formulation Sciences

Answer in Detail

Solved by qualified expert

Get Access to This Answer

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Hac habitasse platea dictumst vestibulum rhoncus est pellentesque. Amet dictum sit amet justo donec enim diam vulputate ut. Neque convallis a cras semper auctor neque vitae. Elit at imperdiet dui accumsan. Nisl condimentum id venenatis a condimentum vitae sapien pellentesque. Imperdiet massa tincidunt nunc pulvinar sapien et ligula. Malesuada fames ac turpis egestas maecenas pharetra convallis posuere. Et ultrices neque ornare aenean euismod. Suscipit tellus mauris a diam maecenas sed enim. Potenti nullam ac tortor vitae purus faucibus ornare. Morbi tristique senectus et netus et malesuada. Morbi tristique senectus et netus et malesuada. Tellus pellentesque eu tincidunt tortor aliquam. Sit amet purus gravida quis blandit. Nec feugiat in fermentum posuere urna. Vel orci porta non pulvinar neque laoreet suspendisse interdum. Ultricies tristique nulla aliquet enim tortor at auctor urna. Orci sagittis eu volutpat odio facilisis mauris sit amet.

Tellus molestie nunc non blandit massa enim nec dui. Tellus molestie nunc non blandit massa enim nec dui. Ac tortor vitae purus faucibus ornare suspendisse sed nisi. Pharetra et ultrices neque ornare aenean euismod. Pretium viverra suspendisse potenti nullam ac tortor vitae. Morbi quis commodo odio aenean sed. At consectetur lorem donec massa sapien faucibus et. Nisi quis eleifend quam adipiscing vitae proin sagittis nisl rhoncus. Duis at tellus at urna condimentum mattis pellentesque. Vivamus at augue eget arcu dictum varius duis at. Justo donec enim diam vulputate ut. Blandit libero volutpat sed cras ornare arcu. Ac felis donec et odio pellentesque diam volutpat commodo. Convallis a cras semper auctor neque. Tempus iaculis urna id volutpat lacus. Tortor consequat id porta nibh.

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Hac habitasse platea dictumst vestibulum rhoncus est pellentesque. Amet dictum sit amet justo donec enim diam vulputate ut. Neque convallis a cras semper auctor neque vitae. Elit at imperdiet dui accumsan. Nisl condimentum id venenatis a condimentum vitae sapien pellentesque. Imperdiet massa tincidunt nunc pulvinar sapien et ligula. Malesuada fames ac turpis egestas maecenas pharetra convallis posuere. Et ultrices neque ornare aenean euismod. Suscipit tellus mauris a diam maecenas sed enim. Potenti nullam ac tortor vitae purus faucibus ornare. Morbi tristique senectus et netus et malesuada. Morbi tristique senectus et netus et malesuada. Tellus pellentesque eu tincidunt tortor aliquam. Sit amet purus gravida quis blandit. Nec feugiat in fermentum posuere urna. Vel orci porta non pulvinar neque laoreet suspendisse interdum. Ultricies tristique nulla aliquet enim tortor at auctor urna. Orci sagittis eu volutpat odio facilisis mauris sit amet.

Tellus molestie nunc non blandit massa enim nec dui. Tellus molestie nunc non blandit massa enim nec dui. Ac tortor vitae purus faucibus ornare suspendisse sed nisi. Pharetra et ultrices neque ornare aenean euismod. Pretium viverra suspendisse potenti nullam ac tortor vitae. Morbi quis commodo odio aenean sed. At consectetur lorem donec massa sapien faucibus et. Nisi quis eleifend quam adipiscing vitae proin sagittis nisl rhoncus. Duis at tellus at urna condimentum mattis pellentesque. Vivamus at augue eget arcu dictum varius duis at. Justo donec enim diam vulputate ut. Blandit libero volutpat sed cras ornare arcu. Ac felis donec et odio pellentesque diam volutpat commodo. Convallis a cras semper auctor neque. Tempus iaculis urna id volutpat lacus. Tortor consequat id porta nibh.

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Hac habitasse platea dictumst vestibulum rhoncus est pellentesque. Amet dictum sit amet justo donec enim diam vulputate ut. Neque convallis a cras semper auctor neque vitae. Elit at imperdiet dui accumsan. Nisl condimentum id venenatis a condimentum vitae sapien pellentesque. Imperdiet massa tincidunt nunc pulvinar sapien et ligula. Malesuada fames ac turpis egestas maecenas pharetra convallis posuere. Et ultrices neque ornare aenean euismod. Suscipit tellus mauris a diam maecenas sed enim. Potenti nullam ac tortor vitae purus faucibus ornare. Morbi tristique senectus et netus et malesuada. Morbi tristique senectus et netus et malesuada. Tellus pellentesque eu tincidunt tortor aliquam. Sit amet purus gravida quis blandit. Nec feugiat in fermentum posuere urna. Vel orci porta non pulvinar neque laoreet suspendisse interdum. Ultricies tristique nulla aliquet enim tortor at auctor urna. Orci sagittis eu volutpat odio facilisis mauris sit amet.

Tellus molestie nunc non blandit massa enim nec dui. Tellus molestie nunc non blandit massa enim nec dui. Ac tortor vitae purus faucibus ornare suspendisse sed nisi. Pharetra et ultrices neque ornare aenean euismod. Pretium viverra suspendisse potenti nullam ac tortor vitae. Morbi quis commodo odio aenean sed. At consectetur lorem donec massa sapien faucibus et. Nisi quis eleifend quam adipiscing vitae proin sagittis nisl rhoncus. Duis at tellus at urna condimentum mattis pellentesque. Vivamus at augue eget arcu dictum varius duis at. Justo donec enim diam vulputate ut. Blandit libero volutpat sed cras ornare arcu. Ac felis donec et odio pellentesque diam volutpat commodo. Convallis a cras semper auctor neque. Tempus iaculis urna id volutpat lacus. Tortor consequat id porta nibh.

31 More Pages to Come in This Document. Get access to the complete answer.

MyAssignmenthelp.com has become one of the top class MBA essay writing services in the USA. Students prefer hiring our essay writing service as we provide affordable services. Despite delivering services at a cheap rate, we never compromise with the quality of our services. We render best quality essay help on more than 100 subjects. Students prefer hiring us, as we deliver solutions on time and have provisions to assist them with fast assignment solutions. Hence, with continuous support from students, we have become one of the top essay writing companies.

More PHAR110 PHAR1101 Introduction to Pharmacy and Formulation Sciences: Questions & Answers

Q

Title: Annotated Literature Review (Remote Dispensing unit/pharmacy) Type: Annotated Literature Review Word Limit: Minimum 1000 words Maximum 1200 words References: Minimum of 15 references Task Description: Write an ANNOTATED literature review for the proposed clinical innovation of a remote dispen ...

View Answer
Q
icon

We aren't endorsed by this University

1.1 What is the organism that causes tetanus and why is it of concern in this situation?1.2 Discuss the rationale for giving Mary the tetanus booster.  2. Physiological basis of the three wound observations 2.1 For each of the three wound observations indicate, and provide a rationale, as to wh ...

View Answer
Q

The assignment requires writing up an ethics essay based on a medical case we have encountered. So far I have two cases that raised ethical questions that I could use. One about euthanasia and another about hormone treatment for a transgender teenager.We can definitely provide more information about ...

View Answer
Q

1. A patient requiring a PEG feed has their digoxin tablets converted to an elixir. The doctor has converted the dose appropriately and prescribed the elixir in the drug chart below. Using the drug chart, how many millilitres of Digoxin Elixir 50mcg/mlis required to administer the required daily dos ...

View Answer

Content Removal Request

If you are the original writer of this content and no longer wish to have your work published on Myassignmenthelp.com then please raise the content removal request.

Choose Our Best Expert to Help You

expert
student rating student rating student rating student rating student rating
Arthur McPherson

MSc in Psychology

928 - Completed Orders

Hire Me
expert
student rating student rating student rating student rating student rating
Woodward Case

Mechanical Engineering from Nanyang Technological University.

600 - Completed Orders

Hire Me
expert
student rating student rating student rating student rating student rating
Daniel McPherson

Pursuing PhD in Nursing with Specialization in Geriatric Nurse

2039 - Completed Orders

Hire Me
expert
student rating student rating student rating student rating student rating
Ezekiel Koch

PhD in Economics

187 - Completed Orders

Hire Me

Still in Two Minds? The Proof is in Numbers!

33845 Genuine Reviews With a Rating of 4.9/5.

student rating student rating student rating student rating student rating
02 Dec 2021

Management

Assignment: 16 Pages, Deadline: 16 days

Very supporting and helpful, I am happy to express that the assignment and writing is very good and helped me to achieve good achievement in study.

flag User ID: 4***58 Malaysia

student rating student rating student rating student rating student rating
02 Dec 2021

Medical

Programming: 4 Pages, Deadline: 2 days

they do so much good, the grades go up and professor are so happy! would definitely recommend

flag User ID: 7***77 United States

student rating student rating student rating student rating student rating
02 Dec 2021

Medical

Course Work: 6.4 Pages, Deadline: 3 days

Very satisfied will definitely go back for more help. Delivered before the deadline

flag User ID: 7***77 United States

student rating student rating student rating student rating student rating
02 Dec 2021

HRM

Assignment: 12 Pages, Deadline: 1 day

Get the good result. And the expert on time to submit it. The suggestion quite good, but if more real life example is will be better and will still us ...

flag User ID: 4***0 Central District, Hong Kong

student rating student rating student rating student rating student rating
02 Dec 2021

Organizational Behavior

Essay: 12 Pages, Deadline: 5 days

Get the good result. And the grade also satisfaction grade. The expert on time to send the assignment, if write more suggestion and real example will ...

flag User ID: 4***0 Central District, Hong Kong

student rating student rating student rating student rating student rating
02 Dec 2021

HRM

Assignment: 10 Pages, Deadline: 5 days

Got the great result and satisfaction grade. Thank you very much. Will still use this service. The expert carefully to write and suggestion, but if m ...

flag User ID: 4***0 Central District, Hong Kong

student rating student rating student rating student rating student rating
02 Dec 2021

Management

Essay: 2 Pages, Deadline: 2 days

The result great and satisfaction. Will still use this service and recommend to my classmates and friends. But if more life examples and suggestion wi ...

flag User ID: 4***0 Central District, Hong Kong

student rating student rating student rating student rating student rating
02 Dec 2021

Management

Assignment: 1 Page, Deadline: 7 days

Excellent work done by the experts. Even they charges less than anyone with the best work. My instructor appreciate me for my work infront of the whol ...

flag User ID: 8***10 Canada

student rating student rating student rating student rating student rating
02 Dec 2021

Project Management

Essay: 1 Page, Deadline: 15 hours

I had to make a couple of edits other than that the assignment was written well.

flag User ID: 7***16 United States

student rating student rating student rating student rating student rating
01 Dec 2021

Marketing

Home Work: 12 Pages, Deadline: 2 days

he did a great job, I receive an A for this exam... I will use this service again.

flag User ID: 7***36 France

student rating student rating student rating student rating student rating
02 Dec 2021

Management

Assignment: 16 Pages, Deadline: 16 days

Very supporting and helpful, I am happy to express that the assignment and writing is very good and helped me to achieve good achievement in study.

flag User ID: 4***58 Malaysia

student rating student rating student rating student rating student rating
02 Dec 2021

Medical

Programming: 4 Pages, Deadline: 2 days

they do so much good, the grades go up and professor are so happy! would definitely recommend

flag User ID: 7***77 United States

student rating student rating student rating student rating student rating
02 Dec 2021

Medical

Course Work: 6.4 Pages, Deadline: 3 days

Very satisfied will definitely go back for more help. Delivered before the deadline

flag User ID: 7***77 United States

student rating student rating student rating student rating student rating
02 Dec 2021

HRM

Assignment: 12 Pages, Deadline: 1 day

Get the good result. And the expert on time to submit it. The suggestion quite good, but if more real life example is will be better and will still us ...

flag User ID: 4***0 Central District, Hong Kong

student rating student rating student rating student rating student rating
02 Dec 2021

Organizational Behavior

Essay: 12 Pages, Deadline: 5 days

Get the good result. And the grade also satisfaction grade. The expert on time to send the assignment, if write more suggestion and real example will ...

flag User ID: 4***0 Central District, Hong Kong

student rating student rating student rating student rating student rating
02 Dec 2021

HRM

Assignment: 10 Pages, Deadline: 5 days

Got the great result and satisfaction grade. Thank you very much. Will still use this service. The expert carefully to write and suggestion, but if m ...

flag User ID: 4***0 Central District, Hong Kong

student rating student rating student rating student rating student rating
02 Dec 2021

Management

Essay: 2 Pages, Deadline: 2 days

The result great and satisfaction. Will still use this service and recommend to my classmates and friends. But if more life examples and suggestion wi ...

flag User ID: 4***0 Central District, Hong Kong

student rating student rating student rating student rating student rating
02 Dec 2021

Management

Assignment: 1 Page, Deadline: 7 days

Excellent work done by the experts. Even they charges less than anyone with the best work. My instructor appreciate me for my work infront of the whol ...

flag User ID: 8***10 Canada

student rating student rating student rating student rating student rating
02 Dec 2021

Project Management

Essay: 1 Page, Deadline: 15 hours

I had to make a couple of edits other than that the assignment was written well.

flag User ID: 7***16 United States

student rating student rating student rating student rating student rating
01 Dec 2021

Marketing

Home Work: 12 Pages, Deadline: 2 days

he did a great job, I receive an A for this exam... I will use this service again.

flag User ID: 7***36 France

5% Cashback

On APP - grab it while it lasts!

Download app now

*Offer eligible for first 3 orders ordered through app!

ribbon
callback request mobile
Have any Query?