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CSB441 Quality Use of Medicines

Question

Answered

Question:

Task:

Analyse the case, identify any potential issues, and provide a possible solution that supports the elements of QUM taking into consideration each of the 4 elements - judicious, appropriate, safe, and efficacious.

Patient Information

Name

Mrs. Francesca Marchetti

Sex

Female

Height

165 cm

Weight

70 kg

Age

78 yrs

 

 

Scenario:

Mrs. Francesca Marchetti is a regular customer and has popped into the pharmacy today to ask your advice. She has had heart troubles for many years now and has been taking two heart drugs (X and Z) and a ‘blood thinner’ (Drug Y). Everything has been well managed. However, this morning she received a phone call from the pathology lab to say that her blood clotting times (time it takes her blood to clot) have been steadily increasing for the last month and to go back to see her GP. She is very worried as she cannot get an appointment with her GP till tomorrow.

Current Medications:

Drug X

Drug Y

Drug Z

Commenced 8 years ago

Commenced 6 years ago

Commenced 4 years ago; ceased one month ago

Oral formulation

Oral formulation

Oral formulation

Hepatic extraction ratio (EH) = 0.1

Hepatic extraction ratio (EH) = 0.9

Hepatic extraction ratio (EH) = 0.5

F=0.9

F=0.1

F=0.5

Most renally excreted unchanged

Renal excretion of inactive metabolites

Some drug excreted renally unchanged

CYP2B6 substrate

CYP2B6 substrate

CYP2B6 inducer

CSB441 Quality Use of Medicines

Answer in Detail

Solved by qualified expert

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Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Hac habitasse platea dictumst vestibulum rhoncus est pellentesque. Amet dictum sit amet justo donec enim diam vulputate ut. Neque convallis a cras semper auctor neque vitae. Elit at imperdiet dui accumsan. Nisl condimentum id venenatis a condimentum vitae sapien pellentesque. Imperdiet massa tincidunt nunc pulvinar sapien et ligula. Malesuada fames ac turpis egestas maecenas pharetra convallis posuere. Et ultrices neque ornare aenean euismod. Suscipit tellus mauris a diam maecenas sed enim. Potenti nullam ac tortor vitae purus faucibus ornare. Morbi tristique senectus et netus et malesuada. Morbi tristique senectus et netus et malesuada. Tellus pellentesque eu tincidunt tortor aliquam. Sit amet purus gravida quis blandit. Nec feugiat in fermentum posuere urna. Vel orci porta non pulvinar neque laoreet suspendisse interdum. Ultricies tristique nulla aliquet enim tortor at auctor urna. Orci sagittis eu volutpat odio facilisis mauris sit amet.

Tellus molestie nunc non blandit massa enim nec dui. Tellus molestie nunc non blandit massa enim nec dui. Ac tortor vitae purus faucibus ornare suspendisse sed nisi. Pharetra et ultrices neque ornare aenean euismod. Pretium viverra suspendisse potenti nullam ac tortor vitae. Morbi quis commodo odio aenean sed. At consectetur lorem donec massa sapien faucibus et. Nisi quis eleifend quam adipiscing vitae proin sagittis nisl rhoncus. Duis at tellus at urna condimentum mattis pellentesque. Vivamus at augue eget arcu dictum varius duis at. Justo donec enim diam vulputate ut. Blandit libero volutpat sed cras ornare arcu. Ac felis donec et odio pellentesque diam volutpat commodo. Convallis a cras semper auctor neque. Tempus iaculis urna id volutpat lacus. Tortor consequat id porta nibh.

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