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401175 Analytic Approaches In Epidemiology

tag 0 Download 3 Pages / 608 Words tag 08-01-2020

Question:

1.The data in the table below are taken from a national health survey, a representative cross-sectional prevalence survey estimating 12-month incidence of a range of risk factors for pancreatitis in addition to socio-demographic variables. Similar questions regarding diabetes status and pancreatitis were asked of participants. An extract of the data is given below, stratified by males and females.

Males

Diabetes

Cases

Participants

No

28

2597

Yes

7

998

Total

35

3595

Females

Diabetes

Cases

Participants

No

24

3949

Yes

4

488

Total

54

4437


Discuss statistical interaction and confounding by sex for the following effect measures:

Absolute measure

-Risk difference

Relative measures

-Risk ratio

-Odds ratio 

2. A prospective cohort study of individuals living in Western Sydney was conducted, investigating the effect of diabetes on the development of pancreatitis over a follow up period of 12 months. The data at the end of the follow-up period for males and females are given below.

Males

 

Pancreatitis

Diabetes

Cases

Participants

No

9

450

Yes

41

675

Total

50

1125

Females

 

Pancreatitis

Diabetes

Cases

Participants

No

45

450

Yes

94

301

Total

139

751

Assume no loss to follow-up and that all participants were followed over the follow-up period.

Discuss statistical interaction and confounding by sex for the following effect measures:

-Risk difference

-Risk ratio

-Odds ratio

In your discussion compare your estimates with those from Question 1. Comment on similarities or differences on effect estimates, and likely reasons for these similarities or differences

3. Propose a causal diagram of the relationship between diabetes and cardiovascular, based on the variables provided above. Provide a narrative description (1 paragraph only) of the causal diagram incorporating findings from your analysis in Question 2.

 
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