Describe about the Heart Statistics for Research?
This brochure is designed for teaching the older adult about a new statin drug. Statins are considered as a class of drugs that is used to reduce the level of cholesterol inside human system by inhibiting an enzyme named HMG-CoA reductase. This enzyme plays a vital role in cholesterol production within the liver that makes almost 70% of total cholesterol inside the human system.
Atheroma is the fundamental cause of different cardiovascular diseases. Cardio vascular diseases bring about by atheroma consist heart attack, angina, stroke and peripheral arterial disease (Shiomi, Yamada & Ito, 2005). In the UK, heart diseases are considered as a main cause of meager health and an immense cause of fatality (Bhf.org.uk, 2015). Therefore designing this patient information brochure is of utmost importance.
What is Cholestrol?
Cholesterol blood tests are performed in order to check the probability of developing stroke or cardiac diseases. If an individual is at the higher risk of developing a heart disease because of increased cholesterol level, then he/she will be generally advised to take statin medicine to diminish the level of cholesterol. Lowering the cholesterol level reduces the chances of cardiovascular diseases.
As of 2010, many statin drugs are on the market. The chosen statin drug is Zocor (trade name) or Simvastatin (generic name) (Spacedoc.com, 2015).
Zocor can be used to treat hypercholesterolemia, reduce the risk of heart disease and can also be used for the treatment of heterozygous familial hypercholesterolemia.
It is an oral antilipemic substance and methylated form of lovastatin. It inhibits HMG-CoA reductase. It is effciicent in lessening total and low-density lipoprotein cholesterol plus apolipoprotein B and plasma triglycerides (Drugbank.ca, 2015).
Simvasatin can cross the blood-brain-barrier. It has a highly bound capacity (almost 95%) to human plasma proteins.
Almost 13% of the dose excretes in urine and 60% in feces.
In case of discontinuation of the therapy can leads to arthralgia, myalgia and gastrointestinal disorders.
Patient may suffer from unexplained muscle weakness, pain and tenderness, memory confusion, dark urination, burning sensation while urinating, swelling, increased thirst and drowsiness. It is not necessary that these side effects are must to occur but it is the patients’ responsibility to inform his/her doctor if he/she is allergic to it. The patient must also inform prior if he/she has a history of alcohol use, kidney and liver disease.
Avoid consume grapefruit juice, drastic alterations in dietary habit and avoid alcohol.
Bhf.org.uk,. (2015). Heart statistics - Research - British Heart Foundation. Retrieved 30 January 2015, from https://www.bhf.org.uk/research/heart-statistics
Davidson, M. (2012). Low-Density Lipoprotein Cholesterol, Non–High-Density Lipoprotein, Apolipoprotein, or Low-Density Lipoprotein Particle. Journal Of The American College Of Cardiology, 60(25), 2616-2617. doi:10.1016/j.jacc.2012.06.065
Drugbank.ca,. (2015). DrugBank: Simvastatin (DB00641). Retrieved 30 January 2015, from https://www.drugbank.ca/drugs/DB00641
Shiomi, M., Yamada, S., & Ito, T. (2005). Atheroma stabilizing effects of simvastatin due to depression of macrophages or lipid accumulation in the atheromatous plaques of coronary plaque-prone WHHL rabbits. Atherosclerosis, 178(2), 287-294. doi:10.1016/j.atherosclerosis.2004.10.024
For years now, MyAssignmenthelp.com is providing affordable essay help to millions of students worldwide. Our essay assistance services have helped us in assisting students with even the toughest essay assignments. We take pride in the fact that we cater the best assistance to search terms like help me with my essay. We offer affordable services in the fastest way possible. For our fast delivering services, students trust us with their urgent essay assignment needs. Two of our most popular essay writing services are maths essay help and English essay help.
Introduction It takes long to develop the dreadful disease, Lung Carcinoma. Where as the changes start taking place immediately after the beginning of consumptio...Read More
Introduction Is the Web-world shifting our common senses? It appears improbable to me, however it’s better to put down that query to progression environmen...Read More
Introduction Race for life is known to be a series of events that are conducted to raise funds for women only. Organization of this event is done is done by the ...Read More
Introduction Obesity has emerged as the most pressing nutritional problem facing the developed world. This trend has occurred over a relatively short perio...Read More
Introduction Obesity has emerged as the most pressing nutritional problem facing the developed world. This trend has occurred over a relatively short period ...Read More