New User? Start here.
Error goes here
Discuss About The Molecular Mechanism Growth Hormone Action?
Insulin hormone is a type of peptide hormones which is synthesised by the beta cells of the pancreas. Insulin is used in the regulation of the carbohydrate and fats metabolism in the body, and also it facilitates the glucose absorption from the bloodstreams to the skeletal muscles.
Insulin has the constructive-metabolic role of stimulating fatty acids, glycogen, and protein synthesis. Insulin controls the process of gluconeogenesis in the liver. Insulin clings to the Insulin receptor (IR) which is a heterotetrameric protein comprising of two extracellular alpha units and two intracellular beta units. The adhering of the insulin hormone to the alpha subunits of the insulin receptor encourages the tyrosine kinase activity internal to the beta subunit of the receptor. The conjugated receptor has the power to auto psychology and phosphorylate and many intracellular substances such as the insulin receptor substrates protein.
Growth hormones antagonizes the insulin’s action on the peripheral tissues such as the liver, skeletal muscles and the adipose tissue therefore increasing the production of the glucose from the liver and skeletal tissues and also aids in the decrease of the glucose uptake from the adipose tissues. Growth hormone-induced lipolysis in the visceral adipose tissue and subsequent increased circulating FFA also interferes with insulin signalling pathways which results to the increase of the plasma glucose levels.
The increase of the plasma glucose level is due to the increased hepatic glucose output and also the reduction of the glucose disposal rate. This results from the Adrenaline-induced suppression of the endogenous insulin secretion. The increased rise of the plasma glucose level ids due to the alternation in response of the liver to epinephrine Adrenaline.
The action of epinephrine is enhanced by simultaneous elevations of glucagon and cortisol. The former increases the magnitude, but not the duration, of the rise in hepatic glucose output induced by epinephrine (Knights, 2013).
Cortisol increases the plasma glucose levels through a metabolic pathway which results in the production of glucose from given non-carbohydrates carbon substances. The increase of the plasmid glucose levels results from the breakdown of the proteins, from the breakdown of lipids such as the triglycerides nursing not the fatty acids. The increase also results from the other metabolisms which includes the pyruvate and lactate. The increase of the blood glucose by Cortisol Is aimed to assist with the metabolism of the protein, carbohydrates and fats and also to supress the immune system.
Cortisol is a naturally occurring glucocorticoid, and in most cases, it comes from cholesterol. The secretion of Cortisol is tightly regulated by the CNS which are very sensitive. Cortisol also activates anti-inflammatory and anti-stress (Greenstein, 2015).
Hormone thyroxin facilitates the production of endogenous glucose and at the same time induces the hepatic insulin resistance. The thyroxin hormones increases the production of glucose through the sympathetic projection to the liver, independently of the circulating glucoregulatory hormones. This shows a unique central pathway for the control of the hepatic glucose metabolism by the thyroxin hormone, which results to the increase of the plasmid glucose levels.
The Thyroid hormone is produced in the thyroid glands which contains follicles through which thyroid hormone is synthesise by iodisation of the tyrosine residues in the glycoprotein. The Thyroid hormone usually regulates the uptake of iodide which is mediated by the iodide/sodium symporter that is followed by some steps which are necessary for metabolic regulation in mammals; it is also required for amphibian metamorphosis. (Howell, 2012).
The impact of glucagon is to make the liver to discharge the glucose which had initially stored in its cells into the bloodstreams. This results into the net increase of the blood glucose. Glucagon is also known to induce the liver and other cells to produce glucose out of the building blocks which are obtained from other nutrients found in the body such as the proteins.
Glucagon is a protein hormone synthesised in the Alpha-cells of the Langerhans of the pancreases. The main function of glucagon is to counteract the actions of insulin. It also stimulates the breaking down of the glycogen into glucose. (Assan, 2016).
Assan, R. (2016). Glucagon II. Berlin: Springer Science & Business Media.
Greenstein, A. (2015). Concise Clinical Pharmacology. Texas: Pharmaceutical Press.
Howell, W. H. (2012). psychology and biophysics. London: Saunders.
Knights, K. M. (2013). Pharmacology for Health Professionals. London: Elsevier Australia.
Pessin, J. E. (2014). Mechanisms of Insulin Action. Texas: Springer Science & Business Media.
Ridderstråle, M. (2017). Molecular mechanism of growth hormone action: involvement of Janus kinase 2, insulin receptor substrate-1 and -2 and phosphatidylinositol 3-kinase in the acute insulin-like effects of growth hormone in primary rat adipocytes. Chicago: Lund Universit
To View this & another 50000+ free samples. Please put
your valid email id.
Earn back the money you have spent on the downloaded sample by uploading a unique assignment/study material/research material you have. After we assess the authenticity of the uploaded content, you will get 100% money back in your wallet within 7 days.
Get Moneyinto Your Wallet
Total 4 pages, 1 USD Per Page
*The content must not be available online or in our existing Database to qualify as
To export a reference to this article please select a referencing stye below:
My Assignment Help. (2019). Molecular Mechanism Growth Hormone Action. Retrieved from https://myassignmenthelp.com/free-samples/molecular-mechanism-growth-hormone-action.
"Molecular Mechanism Growth Hormone Action." My Assignment Help, 2019, https://myassignmenthelp.com/free-samples/molecular-mechanism-growth-hormone-action.
My Assignment Help (2019) Molecular Mechanism Growth Hormone Action [Online]. Available from: https://myassignmenthelp.com/free-samples/molecular-mechanism-growth-hormone-action[Accessed 24 September 2021].
My Assignment Help. 'Molecular Mechanism Growth Hormone Action' (My Assignment Help, 2019) <https://myassignmenthelp.com/free-samples/molecular-mechanism-growth-hormone-action> accessed 24 September 2021.
My Assignment Help. Molecular Mechanism Growth Hormone Action [Internet]. My Assignment Help. 2019 [cited 24 September 2021]. Available from: https://myassignmenthelp.com/free-samples/molecular-mechanism-growth-hormone-action.
The respective sample has been mail to your register email id
* $5 to be used on order value more than $50. Valid for
We have sent login details on your registered email.
Getting academic assistance from MyAssignmenthelp.com is a wise decision. Many students, finding the answer to their queries 'who will Do my essay for cheap' are likely to find our services useful and beneficial. They no longer need to waste their time in typing 'can someone write my essay at cheap price', instead they can hire our cheap essay writers to complete the due papers perfectly within given deadline.
Media article 1:
Klein, A. 2017. Foxes seen climbing at night to track down and eat koalas Retrieved 10 May 2017, from https://www.newscientist.com/article/2120944-foxes-seen-climbing-trees-at-night-to-track-down-and-eat-koalas/
Journal paper 1: Mella, V.S., McArthur, C., Frend, R. and Crowther, M.S., 2017. Foxes in trees: a threat for Australian arboreal fauna?. Australian Mammalogy.
Conservation issue and significanc...
Provide your appraisal of the strengths and weaknesses of the presentation of the statistical material in Fox et al, 2010 against items 10, 12-17 of STROBE
The researchers used a sample of 4746 middle school and high school students. However, it is not clear how the sampling was done. The researchers have not mentioned the sampling techniques they applied, whether simple random, cluster, systematic or stratifie...
Age (in years)
1: < 40 years, 2: 40 - 49 years, 3: 50 – 59 years and 4: >= 60 years
1: Male; 2: Female
1: Sedentary worker; 2: Moderate worker; 3: Heavy physical worker
1: Cells, tissues, organs and systems
Cells are the smallest unit of life, which is independent, composed of a cell membrane, genetic material, cell organelles and cell wall (in plants only). It is the key structural and functional unit of human body that makes up the complex human body structure. Cells are of two types, i.e. prokaryotes and eukaryotes. The prokaryotic cells are primitive cells, like bacteria, consisting cell membran...
Human female germ cells has two X chromosomes and human male has one x and one Y chromosome. If the fertilization occurs via X-bearing sperm results in female offspring and fertilization by Y-bearing or X-deficient sperm results in make offspring. This ability of male gamete to determine the sex of the offspring and the presence of unique Y chromosomes in male gamete lead to the foundation of the paternal testing (Bachtro...
Are you confident that you will achieve the grade? Our best Expert will help you improve your grade
BIOL875 Contemporary Conservation In Australia
BIO101 Molecular And Cellular Biology
SCI3314 Current Issues In Biology
401077 Introduction To Biostatistics
COMR2010 Cultural Diversity A Personal Perspective
MPH5041 Introductory Biostatistics
SK299 Human Biology
Just refer 5 friends to earn more than $2000.
After the successfull payment you will be redirected to the detail page where you can see download full answer button over blur text.You can also download from there.
Or you can also download from My Library section once you login.Click on the My Library icon
My Library page open there you can see all your purchased sample and you can download from there.
That's our welcome gift for first time visitors
It is too easy to create or access your own library, just enter your email and make your search
MyAssignmenthelp.com stores a huge
COLLECTION OF QUESTIONS AND SAMPLES, which you can refer to any time you want.
Every time you find something useful, you can save that using the bookmark tool. From the next time,
can access that from your personalized library.
With this feature, you get to create your own collection of documents. You get free
choose and bookmark any document you wish.
Accessing the collection of documents is absolutely easy. Once you bookmark a sample,
access its content with a few clicks on your mouse.
This personalized library allows you to get faster access to the necessary documents.
longer need to spend hours to locate the sample you need.
Finding a sample from a list of thousands is nothing less than spotting a needle in a
Personalizing your own library relieves you from that stress.
On APP - grab it while it lasts!
*Offer eligible for first 3 orders ordered through app!
ONLINE TO HELP YOU 24X7
OR GET MONEY BACK!
OUT OF 33845 REVIEWS
Received my assignment before my deadline request, paper was well written. Highly