NIT6130 Introduction To Research

Introduction

The literature review in this assignment has been carried out in order to analyze the previous studies on the topic of Human drug trials. The literature review states the problems faced during the trials carried out by professionals. It also states the ethical, security and integrity issues faced by the field of medicine while carrying out drug

Research journal

Filing system

Comprehensive critique

The major problem faced while carrying out the research is that the practical inspection of the challenges faced due to human drug trials cannot be carried out. There are many drug trials that are conducted on random people.

According to Torok, Dranoff & Schuppan (2015), Human Drug Trials are processes that are conducted on people for testing newly introduced drugs. These drugs are tried on people by taking their full consent. A consent paper is signed by the people in order to prove that the person agreed to the terms and conditions of trail. The Human Drug Trials are aimed at evaluating a particular surgical, medical or any behavioral intervention. Human Drug Trials are the ways by which researchers find out various new methods by which a particular disease can be cured. Often Human Drug Trials are very effective and many a times they are not. Trials can be effective as well as might prove to be not effective enough. In some cases, it had been found that a simple mistake during Human Drug Trials have resulted in serious threats for the medicine industry as well as the person who had been selected for the trial. Some Human Drug Trials find out ways by which a disease can be detected early.

Human Drug Trials have various advantages like, it provide the opportunity to professionals to serve the common people. As per Santos, Ursu & Gaulton (2017), the trials help the person selected to get free checkups in order to find out the illness present in him and many more. The person selected for trials is promised free medical care if any negative side effects have been seen due to the trial carried out. The Human Drug Trials might result in many side effects like person on whom trial has been carried out, might have rashes or other medical issues. These issues are to be handled with care.

Subjects

Some subjects that Human Drug Trials include are prospective assignment of human subjects, identification of one or many behavioral or biomedical outcomes that are related to health and one or many interventions.

Instrumentation

Some instrumentations and equipments involved in the Human Drug Trials are instruments for sample separation, genetic analysis, mass spectrometry, cell factory systems, clinical laboratory refrigerators, clinical incubators, clean containers and clinical laboratory freezers.

Data collection, presentation and analysis

Data collection had been carried out through various sources available on internet. Surveys have not been conducted because the detailed data regarding the human drug trials are not disclosed in net or any website. People do not get to know the ones who were selected for the trials. Various journals and articles were read and some were shortlisted from them in order to carry out this study. Some published guidelines obtained from National Library of Medicine’s Medline. The review had been limited to the English Language Articles. Data from various abstracts, posters, retrospective trials, letters, unpublished data and case reports had not been considered. Around 200 papers have been read and from them around 97 had been selected which were more relevant to the research topic. These papers were thoroughly reviewed, analyzed and the final literature review had been prepared.

The result of Human Drug Trials must available to everyone. If the results are not shared, the reason that occurred in delay should be mentioned along with the time when it would be delivered. The inner information regarding how the test was carried out and what were steps that were followed by the professionals should be kept confidential. Human Drug Trials are most of the time beneficial for the medicine industry. It introduces new cure to old diseases.

Research type

The type of research carried out in this paper is the basic type of research. This is because no surveys or experiments had been carried out. This is a basic type of research because the data collected for this research has been obtained from internet sources, books, journals and articles.

Overall evaluation

 People, who make various decisions regarding the needs of health care, do it from the conclusions obtained by studying various trails and their success. The Human Drug Trials should be registered before they are carried out. There should be a transparency in the Human Drug Trials that would be performed. The main aim of the Human Drug Trials is that the outcomes obtained would be helpful to common people and contribute in improving health as well as health care.

References

Santos, R., Ursu, O., Gaulton, A., Bento, A. P., Donadi, R. S., Bologa, C. G., ... & Overington, J. P. (2017). A comprehensive map of molecular drug targets. Nature reviews Drug discovery, 16(1), 19.

Torok, N. J., Dranoff, J. A., Schuppan, D., & Friedman, S. L. (2015). Strategies and endpoints of antifibrotic drug trials: Summary and recommendations from the AASLD Emerging Trends Conference, Chicago, June 2014. Hepatology, 62(2), 627-634.