Telophase is the name which is given to the final stage in the process of both Meiosis and Mitosis taking place within the eukaryotic cell. During this phase, the effects which the prophase and the prometaphase are reversed. As Chromosomes reach the poles of the cell, a nuclear envelope is re-established around each set of the chromatids. Here, the nucleoli reappear and then after the chromosomes begin with their decondensation back into the form of the expanded chromatin that is present during the phase known as the interphase. The mitotic spindle is disassembled and the microtubules of the remaining spindle are depolymerized. Telophase is responsible alone for approximately 2% of the duration which a cell cycles takes to complete.
Cytokinesis specifically begins before the onset of the late telophase and when it gets over, it is responsible for the segregation of the two daughter nuclei between a single pair of daughter cells. Telophase is driven primarily by the dephosphorylation of the mitotic cyclin-dependent kinase related substrates.
Four things that happen during telophase are,
Earlier it was mentioned that within the prophase, the cells cytoskeleton becomes disassembled. The disassembled cytoskeletal related filaments are used in various ways during cytokinesis. Cleavage occurs as a result of the contraction of a thin ring of the action containing filaments that form the specific contractile ring and paves the way for the next phase of the cell division.
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