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MB5021 Bioinformatics

Assessment 1: Oral Presentation: Basic Local Alignment and Pairwise Alignment

Provides critical justifications for performing sequence alignment analyses for the condition/case

Outlines strategies for sequence analysis searching

Able to Perform BLAST or Pairwise searches at the NCBI or EMBL website

Demonstrates understanding of how to vary optional BLAST or Pairwise analysis search parameters

Explains the three phases of a BLAST or Pairwise analysis search (compile, scan/extend, trace?back)

Defines the mathematical relationship between expect values and scores

Able to compare short sequence to a large one; single sequence to an entire database or a partial sequence to the whole.

Identifies newly determined sequences; compare new genes to known ones or guess functions for entire genomes full of ORFs of unknown function.

Uses appropriate tables and figures, in-text citations, reference list, appendix materials to support the results.

Provides fluent, logical and accurate description and or reporting of background knowledge, methods, results and discussions.

Assessment 2: Oral Presentation of Sequence Alignment Analysis
  • Select a topic of your choice, critically justify the choice and perform Basic Local Alignment or Pairwise Alignment analyses
  • State an aim and objectives for the specific analysis.
  • Describe the methods you used coherently to enable replication
  • Provide a critical justification for the method you used to perform the analysis.
  • Coherently and logically present and interpret the results. Use figures and table where appropriate
  • Critically discuss the findings. Cite in-text sources to justify your arguments
  • Provide a complete reference list for the sources cited in your work.

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