Literature Review: Towards Personalized Drug Therapy in the Treatment of Cancer: Now and the Future

On completion of this unit you should be able to

1. Demonstrate the following knowledge and understanding:

How drug development moves from early ‘hits’ through leads to final clinically useful products

2. Demonstrate the following skills and abilities:

The ability to account for the time and financial costs of drug development, its impact on the cost of drugs, and so on accumulated health care costs.

What am I required to do in this assignment?

Students are required to prepare a literature review on

‘Towards personalized drug therapy in the treatment of cancer: Now and the future’.

The assignment should contain a review of peer reviewed scientific literature, including original scientific articles. Peer reviewed review articles may be used as a basis to guide students to appropriate articles and as sources that summarise key findings. All references must be appropriately cited in text and listed in the required format (UoB Harvard) in the reference list. Each topic requires up to date articles to be reviewed, in addition to older articles, which reported key findings in the selected area.

Guidance on the content of this report is given below and will be further discussed during tutorial/lecture sessions

What do I need to do to pass? (Threshold Expectations from UIF)

Submission Deadline Marks and Feedback

20 working days after deadline (L4, 5 and 7)

15 working days after deadline (L6)

10 working days after deadline (block delivery)

Four weeks after the deadline

Assignment number and title Assignment 1: Towards personalized drug therapy in the treatment of cancer: Now and the future

Unit learning outcomes On completion of this unit you should be able to

1. Demonstrate the following knowledge and understanding:

How drug development moves from early ‘hits’ through leads to final clinically useful products

2. Demonstrate the following skills and abilities:

The ability to account for the time and financial costs of drug development, its impact on the cost of drugs, and so on accumulated health care costs.

• Analyse critically the development process of the drug you select.

• Demonstrate, through appropriately cited and germane references, skills in supporting your evaluation of the above.

How do I produce high quality work that merits a good grade?

In order to be awarded a good grade you should follow the following advice regarding report content.

• Consult the table at the end of this brief.

• Present the current, peer-reviewed published knowledge that underpins the topic you are reviewing, ensuring your work is fully referenced.

• Review articles may be used as a basis to guide you to appropriate primary research and as sources that summarise key findings

A typical literature review will include the following sections.

The abstract should summarise your whole review and should be understandable in isolation. It should be in a paragraph format and should

This section should include a short introduction to the topic. You should summarise the published background literature relevant to this study. You should clearly state the scientific aim (s) of your literature review Main body

In this section, you must present in detail the key papers you have found relevant to the topic. Any figures/tables obtained from published source should be fully referenced. All figures/tables must have titles and legends. Ensure that your review is structured using appropriate sub-headings.