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BTEC 635 Clinical Pharmacology

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168.734 Clinical pharmacology

Question

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 Purpose: The analysis of client case reports provides an opportunity to reflect and critically/scientifically analyse a pharmacological intervention provided in the clinical environment to a specific client. Learning outcome/s being assessed: 1, 2, 3, 4, 5 Task: No drug is safe. Therefore the benefits of a drug should outweigh the risks associated with its use. In this assessment, you are required to write a report analysing the benefit/risks of a specific drug and its PK/PD parameters prescribed at a specific point in time/presentation in a fully anonymous client case chosen from your clinical practice. The case analysis in this assignment is retrospective so it does assume that a drug has been prescribed in order for it to analysed in the context of a specific patient/client. The report is intended to be written at a level appropriate to your peers and other medical/health professionals. Instructions: Important: See the requirements for written Assignments (i.e. information on formatting, submission etc). Your report should be one (1) document and consist of: A separate title page (1 page) Your case report: use clearly titled section headings A separate reference page(s) This Assignment is a report (not an essay), so you can include aspects such as a brief Abstract (on the title page), headings/subheadings, clearly explained diagrams, tables, bullet points, appendix (if necessary). The content of the report should include the following: Background: What drug(s) will be analysed in the body of the report? Why do you think this case is important? what is the issue? why you chose to write it up? - Provide a clear and concise rationale that explains the issue/background/choice Case Description: Include a brief patient-specific vignette (300 words) of information that is relevant to the prescription of the drug(s) at the point in time of the client presentation A brief description/history of the presentation (only include essential relevant medical/social/family history) Report the diagnosis/differential diagnosis that justifies the use of the drug that is the focus of the report (do not spend time justifying/explaining the diagnosis) Key symptoms/examinations/investigations relevant to the drug prescribed (include reference ranges where relevant e.g. Laboratory tests) Include a table of all the client's current medications, dose, frequency etc. Remember to include complementary and over the counter medicines. Case Analysis: Using headings/subheadings, include the following in your analysis: Identify/explain and focus on the relevant physiology/pathophysiology/pathogenesis that underpins the pharmacological issue in the context of the client. Be sure to identify/analyse and link the key aspects that are most relevant/pertinent to how the drug(s) restore or manage (patho)physiologic function and provides context to the drug's mechanism of action. Choose 1 (or 2) key drugs relevant to the pharmacological issue used in the treatment of this client. (Note: there may situations where it is logical to analyse more than 2 drugs e.g. triple therapy H. pylori, in which case it would be sensible to do so). For each drug: Discuss the mechanism of action. Concisely/precisely report evidence of efficacy and incidence (rates) of side effects from empirical scientific literature (e.g. RCT's, meta-analysis or observation/pragmatic studies if necessary). In the context of the client explain/discuss the pharmacokinetics. Be thorough and specific using reputable peer-reviewed academic literature and other reputable resources. Discuss the possible side/adverse effects of this drug, relevant drug-drug interactions, contraindications, and client considerations that require attention/monitoring in this client and explain why. Pay particular attention to the side/adverse effects for which the client is at increased risk or may potentially be serious. The mechanisms (e.g. PK/PD) by which these interactions, side/adverse effects occur should be identified and explained. Use reputable peer-reviewed academic literature and other reputable resources. Critical analysis and reasoning should be evident in reporting Use the non-proprietary (non-commercial) names for the drugs Outcome and Follow-Up/Prescriber considerations: Describe the client's response to the pharmacological interventions and actual follow-up received. If this is unknown, discuss the follow-up that might reasonably be expected to have occurred. Discuss prescriber considerations and relevant client advice/education. Explain rationales for your recommendations. Conclusion: Based on an objective critical synthesis of the pharmacological analysis, conclude with a discussion of what was done well and what (if anything) could be improved along with any recommendations/implications you may have identified for practice. Take-Home Messages: In 3 to 5 bullet points summarise the key points you have learned from analysing this client case. References: Use your textbook, reputable peer-reviewed academic literature, and other highly reputable resources (e.g. NZ Formulary, Medsafe, Bpacnz, UptoDate, Martindale).

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NU673 Advanced Pharmacology

Case Study Mrs. A is a 71 year old widow with CHF and osteoarthritis who has recently been exhibiting quite unusual behavior. Her daughter is concerned about her mother's ability to remain independent and wishes to pursue nursing home admission arrangements. She fears the development of a dementing ...

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Psych 2301 The Mind on Drugs

Objective: Identify the states of consciousness cause by different drugs. Points Possible: 50 Steps: 1. Watch the Psych Simulation "Mouse Party" NOTE: You will need Flash Player (Links to an external site.) for this Simulation Activity. If you have issues with this link, use Chrome or FireFox as you ...

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NURS6521N Advanced Pharmacology

Task: 1-Explain how the factor (i.e. genetics, gender, ethnicity, age or behavior) you selected might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study you were assigned. 2-Describe how changes in the processes might impact the patient’s recommend ...

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BTEC 635 Clinical Pharmacology

Task: Instructions. The goal of this assignment is to strengthen scientific writing and primary literature interpretation skills. Students will be assigned a topic or question in the realm of clinical pharmacology and will be expected to write a 4 page concise scientific review on the topic assigne ...

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