You have been provided with excerpts from transcript looking at the experience of being hospitalized. You are to code the transcripts and identify the common themes that emerge. With the themes identified, you are to write up your qualitative findings remembering to tell the story- describe what the theme is, how it appeared and give illustrations supporting what you are describing.
This assignment will develop your skills in data coding and categorization in order to describe the essence or meaning from qualitative data. You are being given short responses from multiple individuals – the actual data set would be much larger.
This is a qualitative study looking at the phenomenon of the “patient experience” while being hospitalized. The purpose of the study is to gather information as to how patients view the experience- what do they perceive as excellent and what do they perceive as problematic. The overall research question is “What is the experience of quality care for adult patients hospitalized in an acute care facility?
- Discuss the similarities and differences between the 4 types of economic evaluations studies (i.e. cost effectiveness, cost utility, cost benefit, and cost minimization).
- The dataset called “DataSetInstrumentsDemographics_Correct” contains data from the HIV/AIDS Targeted Quality of Life (HAT-QoL) instrument (Bakken et al., 2000) for the variable HATTOT, which is a measure of the quality of life of HIV positive patients with regards to living with AIDS. Based on this data, the mean HATTOT score for the sample was 97.8. The possible range of raw scores for the HATTOT variable is 29 to 145, with higher scores indicating better mastery of the illness and fewer symptoms. It was also found that the mean number of years patients have lived with AIDS in this sample is 17.7 years.
Using this information, calculate the quality of life index for this sample.
Calculate the mean quality-adjusted life years (QALYs) for the sample. - Suppose a new intervention to improve the quality of life of HIV positive patients is developed, and it is studied in an experimental study involving the same patients in this sample. Some patients received this new intervention (experimental group), while some received no intervention (control group). Consider the mean number QALYs calculated in question 2b to be the baseline measure of quality of life before the intervention is implemented for both groups. Twenty years later the quality of life of these patients is measured again, and at the conclusion of the study, the investigators measured the final mean QALYs in both groups. Table 1 below shows the results of this experiment.
Table 1. Number of QALYs at baseline and 20 years after the implementation of a new intervention to improve the quality of life of HIV positive patients.
QALYs at baseline |
QALYs at study end |
Statistical Significance |
|
Experimental group |
As per question 2b above |
18 |
p < 0.05, t-test for independent samples |
Control group |
Same baseline as experimental group |
13.5 |
What is the mean change in QALY that resulted from the experimental treatment? Be sure to also interpret this result in terms of statistical significance and what this means in practical terms.
- In addition to the information in question 3, you are given the information shown in Table 2 regarding the costs associated with the treatment and control groups over the 20 years of the experiment.
Table 2. 20-year average costs associated with each group in this study per participant.
Experimental Group |
Control Group |
|
Drug costs for the new treatment |
$5000 |
$0 |
Cost of supply materials to deliver new treatment |
$1000 |
$0 |
Lost productivity at work |
$1000 |
$6000 |
Hospital personnel costs |
$2000 |
$6000 |
Clinic healthcare costs |
$1500 |
$2000 |
Intangible costs (estimated based on patient survey and qualitative research) |
$1500 |
$4000 |
Based on all this information, calculate the following for each group:
- The financial cost of the treatment
- The direct cost of the treatment
- The societal cost of the treatment
- The incremental cost per QALY, based on the financial cost model
- The incremental cost per QALY, based on the direct cost model
- The incremental cost per QALY, based on the societal cost model
- What are the benefits and limitations of using one of these incremental cost per QALY results over the others? Be sure to use your results from question 4 in your discussion.
- Suppose you live in a society where it has been agreed that spending $1000 for each additional QALY gained is well worth the expense, and policy decisions are made on the basis of this cutoff value. Based on the results of question 4, would you implement this new intervention for HIV positive patients living with AIDS? Be sure to explain your reasoning.
Coding and Categorization for Qualitative Findings
Cost Minimization looks at a comparison of the alternative programs in which all the relevant alternative measures are of equal measure for example, it may look at whether two projects provide an equal level of effectiveness (Graban, 2011).
In the case of cost effectiveness, both the alternatives and measures are taken in consideration. For example, it may take into consideration the measure of effectiveness as well as the alternatives such as incentives or price reduction.
A cost utility analysis is similar to a cost effectiveness analysis. However, it considers a more generic outcome especially among the patients such as the healthy years equivalent or the quality adjusted years. It is mostly useful when there a program has multiple objectives such as quality and quantity (Pett, 2015).
Also, the cost benefit analysis considers alternatives with the use of an expected monetary outcome. It is useful when there are multiple objectives just as that in Cost Utility analysis. The main difference is that a cost benefit analysis is more objective while a cost utility analysis is more subjective (Munro, 2005).
Using this information, calculate the quality of life index for this sample.29/145 =20% (Low range)
145/145 = 100% (High Range)
HATTOT score = 97.8/145 (Quality of life score)
= 0.674
Calculate the mean quality-adjusted life years (QALYs) for the sample.
Years of Life * Utility Value
= 17.7 QALYs
= 17.7 * 0.674
= 11.86 QALYs
Table 1. Number of QALYs at baseline and 20 years after the implementation of a new intervention to improve the quality of life of HIV positive patients.
QALYs at baseline |
QALYs at study end |
Statistical Significance |
|
Experimental group |
As per question 2b above |
18 |
p < 0.05, t-test for independent samples |
Control group |
Same baseline as experimental group |
13.5 |
What is the mean change in QALY that resulted from the experimental treatment? Be sure to also interpret this result in terms of statistical significance and what this means in practical terms.
Experimental group: (18- 11.86)
= 6.141
control group (13.5-11.86)
=1.64
average of experimental group by control group
= 4.5
Since the value is less than the P value of 0.05, we reject the null hypothesis that the results of the experimental group are not statistically significant. This means that the results of the experimental group could imply that the intervention might work as a new treatment.
Table 2. 20-year average costs associated with each group in this study per participant.
Experimental Group |
Control Group |
|
Drug costs for the new treatment |
$5000 |
$0 |
Cost of supply materials to deliver new treatment |
$1000 |
$0 |
Lost productivity at work |
$1000 |
$6000 |
Hospital personnel costs |
$2000 |
$6000 |
Clinic healthcare costs |
$1500 |
$2000 |
Intangible costs (estimated based on patient survey and qualitative research) |
$1500 |
$4000 |
Based on all this information, calculate the following for each group:
- The financial cost of the treatment
Experimental Group |
Control Group |
|
Drug costs for the new treatment |
$5000 |
$0 |
Cost of supply materials to deliver new treatment |
$1000 |
$0 |
Hospital personnel costs |
$2000 |
$6000 |
Clinic Healthcare costs |
$1500 |
$2000 |
Total Financial Costs |
$9500 |
$8000 |
Total Financial Costs |
$17500 |
- The direct cost of the treatment
Experimental Group |
Control Group |
|
Drug costs for the new treatment |
$5000 |
$0 |
Cost of supply materials to deliver new treatment |
$1000 |
$0 |
Total Direct Costs |
$6000 |
$0 |
Total Direct Costs |
$6000 |
- The societal cost of the treatment
Experimental Group |
Control Group |
|
Lost productivity at work |
$1000 |
$6000 |
Intangible costs (estimated based on patient survey and qualitative research) |
$1500 |
$4000 |
Total Societal Costs |
$2500 |
$10000 |
- The incremental cost per QALY, based on the financial cost model
Experimental Group |
Control Group |
|
Total Financial Costs |
$9500 |
$8000 |
Incremental cost per QALY |
$9500/11.86 |
$8000/11.86 |
=$801.01 |
$874.53 |
- The incremental cost per QALY, based on the direct cost model
Experimental Group |
Control Group |
|
Total Direct Costs |
$6000 |
$0 |
Incremental cost per QALY |
$6000/11.86 |
$0/11.86 |
$505.90 |
$0 |
- The incremental cost per QALY, based on the societal cost model
Experimental Group |
Control Group |
|
Total Societal Costs |
$2500 |
$10000 |
Incremental cost per QALY |
$2500/11.86 |
$10000/11.86 |
$210.79 |
$843.17 |
Benefits- The benefit of an incremental financial cost per QALY allows the healthcare provide to calculate the cost benefit of implementing a health treatment in an objective manner (Horton , 2007). For example it is clear that the experimental group has a higher incremental cost compared to the control group.
Limitations- While the method offers a subjective view of the health treatment intervention it does not account for its utility and effectiveness. For example the incremental financial costs calculated may be higher than the actual associated costs given other costs are factored in.
Benefits- The direct incremental costs can reveal to what extent does the health intervention affects various departments of a hospital or healthcare facility (Scott & Mazhindu, 2014) .
Limitation- One limitation may be that the direct costs give a limited view of the impact of the health intervention towards other aspects of implementing the treatment.
Benefits- Largely the societal incremental costs look at the nature of quality of life affected by individuals who participate in the health treatment.
Limitations- One major limitation is that the societal costs are highly subjective and may fail to provide the required objective outlook of the treatment (Buckley & Van Glezen, 2004).
It may not be reasonable to implement such a decision. This is because for all the associated costs involved are less than $1000. Therefore the budgeted incremental cost per QALY is higher than that which is reasonably estimated. It may therefore make more sense to implement an intervention which is nearly $600 per QALY.
References
Buckley, J. E., & Van Glezen, R. W. (2004). Federal statistics on healthcare benefits and cost trends: an overview. Monthly Lab. Rev., 127, 43.
Graban, M. A. R. K. (2011). Statistics on healthcare quality and patient safety problems–errors & harm. Retrieved May, 26, 2011.
Horton, L. A. (2007). Calculating and reporting healthcare statistics. American Health Information Management Association.
Munro, B. H. (2005). Statistical methods for health care research (Vol. 1). Lippincott Williams & Wilkins.
Pett, M. A. (2015). Nonparametric statistics for health care research: Statistics for small samples and unusual distributions. Sage Publications.
Scott, I., & Mazhindu, D. (2014). Statistics for healthcare professionals: An introduction. Sage.
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