Principles of Epidemiology:
Select an epidemiology-related topic that interests you and specify a research question.
1. Provide a short literature review of your topic and explain the topic’s importance to health care, public health, etc.
2. Specify the study design that you will use to answer your research question and justify your rationale for choosing that design. Be sure to discuss the advantages and disadvantages of your design relative to other possible study designs. Note: do not simply provide a generic list of advantages and disadvantages. Tailor the discussion to your specific research question. (For example, if you are proposing a case-control study to investigate the association between some exposure and coronary heart disease (CHD) in a hospital setting, then citing the rare disease assumption as an advantage of case-control studies would not be applicable to your specific circumstances because CHD is not a rare disease.)
3. Explain your criteria for enrolling participants (e.g., must be disease-free upon enrollment, each matched control must have the same age and sex as the corresponding case, etc.).
4. Explain how you will measure your exposure and disease (outcome) variables (e.g., score on a specialized scale, clinical diagnostic or screening test result, etc.). Specify your measure of association.
5. Describe the types of biases that might affect your study and outline the strategies that you will employ to minimize these biases.Note: Tailor the discussion to your specific research question and study design.
6. What variables might be potential effect modifiers or confounders in your study? How will you assess effect modification and control for confounding? Note: Tailor the discussion to your specific research question and study design.
7. Tables and figures are not necessary, but you may add up to two tables and two figures.