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CEA301 Human Genetics

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Questions:

1.Name some ethical issues that will be discussed in this Human Genome video?
 
2.Briefly describe characteristics of the human genome mentioned in this segment (base pairs; % coding for actual genes; % we are identical with each other.) About how long did it take to identify the genes for cystic fibrosis and Huntington’s disease?
 
3.A change in how many DNA base pairs (letters) cause Tay-Sachs disease?What goes wrong in Tay-Sachs Disease?

4.Contrast approaches of Human genome project by Celera and Government. Should the government put our taxpayer-derived research for free access even to the competition?Do you think Is it worth the public investment?

5. Discuss the DNA evidence showing that we are highly related to each other and all species including worms and bananas (about what % are we related to these species?). How identical genetically are any two humans?

Do you think it is interesting that we are so often judged based upon our personal appearance but we would be basically indistinguishable from one another based upon our genetic code? Explain your answer.

6.When was gene for cystic fibrosis found? Any cure yet?  Genes and gene products (proteins) interact with one another. Explain how this and the human genome project may help scientists determine better treatments/cures for diseases like CF.

7.What makes Iceland a good country for exploring DNA genome data to find new disease genes? What company was founded here to do this?

Discuss the potential benefits and dangers of DNA databases in combination with health and family records. What protections of privacy must be guaranteed?

8.Describe 1. What is the approximate risk of a woman (US) getting breast cancer in her lifetime? What is the risk if she has inherited a mutation in the BRCA1 or BRCA2 gene? If you were faced with situation of Alana, what would you do? Would you want to be tested for the mutation of this or some other disease if there was no known cure? Take a survey of other students/friends/family and give some reasons for their answers

9.Briefly describe what Assisted reproductive technologies (ART) are currently being done. How far do you think is good?( Choosing sex of baby?Making sure baby has no diseases? Choosing superior strength or intelligence?
 
10.Briefly describe the outcome of the “race” between the government and Celera for sequencing the human genome.

Briefly describe the basic characteristics the video describes about what was discovered about the human genome from this effort (Include the overall “landscape” of our chromosomes; how are genes distributed across the genome? What at % of the genome has known genes that encode proteins? What is selfish” DNA??
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